Bupropion DESCRIPTION:
Bupropion - ORAL (byou-PRO-pee-on)
COMMON Bupropion BRAND NAME(S): Wellbutrin
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What is Bupropion:
Bupropion (Wellbutrin, Wellbutrin SR, Wellbutrin XL) is
taken to treat depression. Bupropion is in a class of
medications called antidepressants. Bupropion works by
increasing certain types of activity in the brain.
Taking Bupropion: Bupropion comes as a tablet and a
sustained-release or extended-release (long-acting) tablet
to take by mouth. The regular tablet (Wellbutrin) is usually
taken three or four times times a day, with doses at least 6
hours apart. The sustained-release tablet (Wellbutrin SR,
Zyban) is usually taken twice a day, with doses at least 8
hours apart. The extended-release tablet (Wellbutrin XL) is
usually taken once daily in the morning. To help you
remember to take bupropion, take it around the same time
every day. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain any
part you do not understand. Take bupropion exactly as
directed. Do not take more or less of it or take it more
often than prescribed by your doctor. Swallow the
sustained-release and extended-release tablets whole; do not
split, chew, or crush them. Your doctor will probably start
you on a low dose of bupropion and gradually increase your
dose. It may take 4 weeks or longer before you feel the full
benefit of bupropion. Continue to take bupropion even if you
feel well. Do not stop taking bupropion without talking to
your doctor. Your doctor will probably decrease your dose
gradually. Your doctor or pharmacist will give you the
manufacturer’s patient information sheet when you begin
treatment with bupropion. Read the information carefully and
ask your doctor or pharmacist if you have any questions.
Bupropion is also sometimes used to treat bipolar depression
and attention deficit disorder. Talk to your doctor about
the possible risks of using Bupropion for your condition.
Bupropion may be prescribed for other uses; ask your doctor
or pharmacist for more information.
Bupropion Precautions and Warnings: Before taking
bupropion, tell your doctor and pharmacist if you are
allergic to bupropion or any other medications. Do not take
bupropion if you are taking monoamine oxidase (MAO)
inhibitors, including phenelzine (Nardil) and
tranylcypromine (Parnate), or have taken them within the
past 14 days. Do not take Wellbutrin, Wellbutrin SR, or
Wellbutrin XL and Zyban together. Tell your doctor and
pharmacist what other prescription and nonprescription
medications, vitamins, nutritional supplements, and herbal
products you are taking. Be sure to mention any of the
following: amantadine (Symmetrel); beta blockers such as
atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor,
Toprol XL), nadolol (Corgard), and propranolol (Inderal);
cyclophosphamide (Cytoxan, Neosar); diet pills; insulin or
oral medications for diabetes; medications for irregular
heartbeat such as flecainide (Tambocor) and propafenone (Rythmol);
medications for mental illness such as haloperidol (Haldol),
risperidone (Risperdal), and thioridazine (Mellaril);
medications for seizures such as carbamazepine (Tegretol),
phenobarbital (Luminal, Solfoton), and phenytoin (Dilantin);
levodopa (Sinemet, Larodopa); nicotine patch; oral steroids
such as dexamethasone (Decadron, Dexone), methylprednisolone
(Medrol), and prednisone (Deltasone); orphenadrine (Norflex);
other antidepressants such as desipramine (Norpramin),
fluoxetine (Prozac), imipramine (Tofranil), nortriptyline (Aventyl,
Pamelor), paroxetine (Paxil) and sertraline (Zoloft);
sedatives; sleeping pills; and theophylline (Theobid, Theo-Dur,
others). Your doctor may need to change the doses of your
medications or monitor you carefully for side effects. tell
your doctor if you have or have ever had, or anyone in your
family has or has ever had, depression, bipolar disorder
(mood that changes from depressed to abnormally excited), or
mania (frenzied, abnormally excited mood), or if you have ,
or anyone in your family has, thought about or attempted
suicide. Also tell your doctor if you drink large amounts of
alcohol or have a drug addiction and if you have or have
ever had seizures; an eating disorder (anorexia, bulimia);
head injury; brain tumor; high blood pressure; liver,
kidney, or heart disease. tell your doctor if you are
pregnant, plan to become pregnant, or are breast-feeding. If
you become pregnant while taking bupropion, call your
doctor. you should know that bupropion may make you drowsy.
Do not drive a car or operate machinery until you know how
Bupropion affects you. minimize or avoid drinking alcoholic
beverages while you are taking bupropion. Alcohol can make
the side effects from bupropion worse. you should know that
your mental health may change in unexpected ways, especially
at the beginning of your treatment and at any time your dose
is increased or decreased. These changes may occur at any
time if you have depression or other mental illness, whether
or not you are taking sertraline or any other medication.
You, your family, or your caregiver should call your doctor
right away if you experience any of the following symptoms:
new or worsening depression; thinking about harming or
killing yourself, or planning or trying to do so; extreme
worry; agitation; panic attacks; difficulty falling or
staying asleep; irritability; aggressive behavior; acting
without thinking; severe restlessness; and frenzied,
abnormal excitement. Be sure that your family or caregiver
knows which symptoms may be serious so they can call the
doctor when you are unable to seek treatment on your own.
Missed Bupropion Dose: Take the missed dose as soon
as you remember it. However, if it is almost time for the
next dose, skip the missed dose and continue your regular
dosing schedule. Do not take a double dose to make up for a
missed one.
Possible Side Effects of Bupropion: Bupropion may
cause side effects. Tell your doctor if any of these
symptoms are severe or do not go away: drowsiness,
restlessness, excitement, anxiety, dry mouth, difficulty
falling asleep or staying asleep, dizziness, headache, upset
stomach, vomiting, tremor, weight loss, constipation,
excessive sweating, Some side effects can be serious.
The following symptoms are
uncommon, but if you experience any of them or those listed
in the IMPORTANT WARNING section, call your doctor
immediately: seizure, confusion, seeing things or hearing
voices that do not exist (hallucinating), irrational fears,
fever, severe skin rash, itching, hives, swelling of the
face, throat, tongue, lips, eyes, hands, feet, ankles, or
lower legs, hoarseness, difficulty breathing or swallowing,
chest pain, muscle or joint pain, rapid, pounding, or
irregular heartbeat. Bupropion may cause other side effects.
Call your doctor if you have any unusual problems while
taking Bupropion.
Storing Bupropion: Keep Bupropion in the container it
came in, tightly closed, and out of reach of children. Store
it at room temperature and away from excess heat and
moisture (not in the bathroom). Throw away any medication
that is outdated or no longer needed. Talk to your
pharmacist about the proper disposal of your medication.
Overdose of Bupropion: Symptoms of overdose may
include: difficulty breathing or swallowing, dizziness,
fainting, shakiness, sweating, confusion, blurred vision,
seizure
seeing things or hearing voices that do not exist
(hallucinating), loss of consciousness, rapid or pounding
hearbeat, blurred vision, lightheadedness, confusion, lack
of energy, upset stomach, jitteriness
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IMPORTANT NOTE: This information is intended to
supplement, not substitute for, the expertise and judgment of
your physician, pharmacist or other healthcare professional.
It should not be construed to indicate that use of the
drug is
safe, appropriate, or effective for you. Consult your
healthcare professional before using Bupropion.